Fish oil "
There are two different types of fish oils – those that come from the liver of ‘lean’ fish such as cod, and those that are extracted from the flesh of fatty fish such as mackerel, herring, or salmon. Fish oils have a high content of fatty acids, with 20 or more carbon chains that are either predominantly monounsaturated, or polyunsaturated with five or six double bonds belonging to the n-3 family. Fish liver oils also contain large amounts of vitamins A and D and are available as oil or in capsules as a dietary supplement of these vitamins. Fish body oils are usually purified and supplements do not generally contain the vitamins.
Many years ago it was observed that Greenland Inuit had a low incidence of coronary heart disease despite their high fat and cholesterol intakes. Most of the fat was from marine foods, with large quantities of the long-chain n-3 fatty acids eicosapentanoate (EPA) and docosahexanoate (DHA) and
research has now demonstrated that these fatty acids affect blood clotting mechanisms so that blood clots that might block coronary arteries narrowed by atherosclerosis are less likely to form. These effects are seen with purified fish oils as well as when fatty fish are consumed. In the UK it had previously been recommended that adults consume two to three portions of fatty fish each week, but fish consumption is generally much lower than this. Recently the UK Food Standards Agency recommended that only two portions of
fish, one white and one oily, be eaten per week. Shark,
swordfish, and marlin may be contaminated with mercury
and should not be eaten by pregnant women, women who
intend to become pregnant, and infants and children under
16. Purified fish oils represent a way of obtaining the n-3
fatty acids, but care should be taken to keep to recommended
doses. As with plant foods, the foods themselves
may contain other, as yet unknown, substances that could also have important effects.
The Joint Health Claims Initiative has assessed the evidence
that consumption of the types of long-chain fatty
acids found in fish oils benefits heart health and in 2005
agreed that foods containing these may use the following
generic claim. ‘Eating 3g weekly, or 0.45g daily, long chain
omega-3 polyunsaturated fatty acids, as part of a healthy
lifestyle, helps maintain heart health.’
Important caveats to the use of the claim are that it
relates only to very long chain polyunsaturated fatty acids
(of chain length 20 carbons or above) including EPA, and
DHA, and not all long chain polyunsaturated fatty acids,
such as alpha-linolenic acid (which have chain lengths of
less than 20). The ratio of EPA and DHA should reflect that
which occurs naturally in oily fish’ and include the statement
that ‘The Government advises that at least 2 servings of
fish, one of which should be oily, containing approximately 3g
LC n-3 PUFA, is consumed each week’ Manufacturers of supplements
should also point out that oily fish is an alternative
supplier of the long-chain n-3 fatty acids. The Food and
Drug Administration in the USA has also allowed a qualified
health claim for n-3 fatty acids and heart health.
There has been much recent interest in the idea that
supplements of long-chain n-3 fatty acids may improve
behaviour and reading and spelling ability in some children,
specifically those with a condition called developmental
coordination disorder. Although there is evidence that these
fatty acids are important in pre-natal brain development
and for post-natal development in premature infants more
research is needed to clarify the possible cognitive benefits in
older children and in the elderly.
Some studies have suggested that consumption of long-chain n-3 polyunsaturated fatty acids may help
protect against diabetes (incidence is lower in populations
with high fatty fish intakes), and may lower blood
pressure in patients with hypertension. Fish oil supplements
(fish liver oils as well as fish body oils) have been
shown in some studies to reduce pain and inflammation
in rheumatoid arthritis, although more research is
needed here. Trials of fish oils in the treatment of skin
diseases such as atopic (allergic) eczema and psoriasis
have shown mixed results. Fish oils do not seem to have
much effect on eczema, but they have been shown to
have modest beneficial effects on psoriasis, especially
when taken in conjunction with other treatments, as
they may alleviate some of the side-effects of drug treatments.
If you are receiving medical treatment for any of
these disorders it is advisable to see your doctor before consuming
fish oil supplements.
11/26/2008
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